A 6-year-old child with Leber’s Congenital Amaurosis (LCA), a rare eye condition that often leads to total vision loss, had her sight restored following cutting-edge gene therapy at London’s Great Ormond Street Hospital. Saffie Sandford’s treatment with Luxturna, which involved injecting both eyes with healthy copies of the RPE 65 gene, was the first demonstration that gene therapy can strengthen visual pathways in a child with LCA. It “restored her sight in the dark,” said Saffie’s mother, Lisa Sandford.