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17 April, 2026
US Deals Outlook 20226: What's ahead for pharma and life sciences
US biopharma still leads the world in high-risk drug development, but the road from innovation to access has never been harder to predict. Hear from top executives and investors on how they’re navigating what’s next. Join us.
spotlight
top stories
1. New CDC pick is lauded by public health pros, lamented by vaccine skeptics
2. Biovac gets $108M backing for vaccine factory in South Africa
3. Q&A: On IPO day, Kailera CEO Ron Renaud talks about obesity market, China and biotech sentiment
4. Pancreatic cancer data, the RAS bonanza and China ADC standouts are ready for AACR
5. Lilly’s tirzepatide sheds lean muscle harder than Novo’s semaglutide, study suggests
6.
peer review
Novartis' Vas Narasimhan heads to Anthropic's board; Metsera alum joins Structure as COO
7. How expensive would a Revolution Medicines buyout be after its Phase 3 win?
more stories
 
news briefing
 
Nicole DeFeudis
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Eli Lilly's weight loss pill Foundayo racked up around 1,390 prescriptions in its first week on the US market, Leerink analysts said on Friday, citing data from IQVIA. The data, first reported by Reuters, appear to fall below early launch data for Novo Nordisk's rival Wegovy pill. But it's difficult to compare at this point, as analysts have said the launch data may be missing certain patients. A fierce match-up is brewing, and Lilly has made clear it came ready to compete.

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Nicole DeFeudis
Editor, Endpoints News
@Nicole_DeFeudis
1
by Max Bayer

Pres­i­dent Don­ald Trump has picked Er­i­ca Schwartz, a for­mer deputy sur­geon gen­er­al and Coast Guard vet­er­an, to be the next CDC di­rec­tor — a like­ly for­ti­fy­ing pick af­ter a year of near-con­stant in­sta­bil­i­ty for the agency.

Trump said in a Truth So­cial post Thurs­day that Schwartz “is a STAR!” Long­time pub­lic health pro­fes­sion­als agreed, ap­plaud­ing the pick in so­cial me­dia posts. The CDC has been with­out per­ma­nent lead­er­ship for al­most the en­tire­ty of Trump's sec­ond term, dur­ing which the child­hood vac­cine sched­ule was over­hauled, an­ti-vac­cine ad­vo­cates were giv­en key posts, and the agency head­quar­ters was at­tacked. With Schwartz as the new pick for di­rec­tor, in­fec­tious dis­ease ex­perts and pub­lic health pro­fes­sion­als fi­nal­ly ex­pressed ap­pre­ci­a­tion.

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2
by Anna Brown

Bio­vac’s new vac­cine fac­to­ry in Cape Town, which is ex­pect­ed to make up to 400 mil­lion vac­cines per year, has se­cured fi­nanc­ing from the Eu­ro­pean In­vest­ment Bank, the Eu­ro­pean Com­mis­sion and the In­ter­na­tion­al Fi­nance Cor­po­ra­tion.

The to­tal cost of the fa­cil­i­ty will be $180 mil­lion, Bio­vac’s CEO More­na Makhoana told End­points News in an email. The fac­to­ry will be lo­cat­ed at Bio­vac's cam­pus in Pinelands, Cape Town.

The fa­cil­i­ty will ini­tial­ly make oral cholera vac­cines and will ex­pand in­to po­lio, pneu­mo­nia and menin­gi­tis vac­cines. Once com­plet­ed, the site will pro­duce be­tween 30 and 40 mil­lion cholera vac­cine dos­es per year, which will ad­dress around 40% of the glob­al cholera vac­cine sup­ply gap.

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3
by Drew Armstrong

On Fri­day, Kail­era Ther­a­peu­tics raised a record-set­ting $625 mil­lion through an IPO on the Nas­daq. Found­ed with back­ing from Bain Cap­i­tal Life Sci­ences, and a pipeline of obe­si­ty as­sets from Chi­na's Hen­grui Phar­ma, the com­pa­ny could be one of the best case stud­ies of what biotech looks like in 2026.

Kail­er­a's new shares KL­RA be­gan trad­ing Fri­day af­ter­noon, and quick­ly gained more than 50%. End­points News Ex­ec­u­tive Ed­i­tor Drew Arm­strong in­ter­viewed CEO Ron Re­naud just a few hours pri­or, and they talked about build­ing the com­pa­ny, part­ner­ing with Chi­na and what Re­naud thinks the IPO tells us about where the sec­tor is go­ing.

This in­ter­view has been edit­ed and con­densed for clar­i­ty.

Drew Arm­strong: Af­ter a few pret­ty gloomy years in biotech, in­vestors seem re­al­ly in­ter­est­ed right now. What changed?

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4
by Lei Lei Wu

The on­col­o­gy field is buzzing af­ter a land­mark read­out from Rev­o­lu­tion Med­i­cines, known col­lo­qui­al­ly as RevMed, showed that a tar­get­ed "pan-RAS" drug dou­bled the sur­vival time for pa­tients whose pan­cre­at­ic can­cer has re­turned or stopped re­spond­ing to pre­vi­ous treat­ment. As can­cer re­searchers and drug­mak­ers head to San Diego this week­end for the an­nu­al AACR meet­ing, here’s what we’re watch­ing:

RevMed will be re­port­ing more da­ta at AACR, both on its drug darax­on­ra­sib as well as an­oth­er KRAS-tar­get­ed ther­a­py zoldon­ra­sib. The Phase 1/2 darax­on­ra­sib read­out will give an up­dat­ed look at how the drug fares as a first-line treat­ment in metasta­t­ic pan­cre­at­ic can­cer, both alone and along­side chemother­a­py. Rev­o­lu­tion Med­i­cines re­port­ed an ini­tial cut of da­ta in the first-line set­ting last year, show­ing over­all re­sponse rates of 47% and 55% alone and with chemother­a­py re­spec­tive­ly.

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5
by Ayisha Sharma

While Eli Lil­ly’s tirzepatide helps pa­tients drop more weight than No­vo Nordisk’s semaglu­tide, this might come with greater loss in lean body mass, ac­cord­ing to a new study await­ing peer re­view.

The analy­sis, shared as a