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The Conversation

We’re now into Day 3 of the new Middle East conflict, and a few things are becoming clearer.

First off, the U.S. and Israeli airstrikes on Iran have set off a series of reactions – economic, political and military – that will undoubtedly change the region. In the short term, travel has been disrupted, the price of oil has spiked, and much of the Gulf region has been placed on high alert. The long term is harder to predict: Where does Iran go after the death of Supreme Leader Ayatollah Ali Khamenei? What are the political risks back home for U.S. President Donald Trump?

In our opening tranche of stories this weekend, The Conversation U.S. focused on answering how we got here and what it all means. The failure of the Iran nuclear talks was, as nuclear proliferation expert Nina Srinivasan Rathbun writes, all too predictable. But, she argues, that did not mean diplomacy wasn’t working: “Under situations of increased military brinkmanship, talks could have helped the U.S. and Iran step back from the edge, build trust and perhaps develop better political relations – even if an actual deal remained out of reach.”

Of course, the stated aims of the U.S. and Israeli governments now go beyond that being discussed by negotiators in the nuclear talks. Rather, they want regime change. Javed Ali, a former senior adviser at the National Security Council, notes that this gives context to Iran’s response. Faced with an existential threat, the regime in Tehran will show none of the restraint it displayed during previous strikes on its assets. “Now the gloves are off, and each side will be trying to land a knockout blow,” Ali concludes.

Also today:

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Matt Williams

Senior International Editor

A plume of smoke rises above Tehran on Feb. 28, 2026. AFP via Getty Images

Iran will respond to US-Israeli strikes as existential threats to the regime – because they are

Javed Ali, University of Michigan

The latest attack on Iran goes far beyond previous operations by Israel and the US in both scale and scope. Tehran will likely lean on unconventional warfare as well as its missile stockpile.

Failure of US‑Iran talks was all too predictable — but turning to military strikes creates dangerous unknowns

Nina Srinivasan Rathbun, University of Toronto; USC Dornsife College of Letters, Arts and Sciences

Silence from the US side after a third round of indirect talks and frustration expressed by President Donald Trump set the stage for military strikes.

Strait of Hormuz: if the Iran conflict shuts world’s most important oil chokepoint, global economic chaos could follow

Sarah Schiffling, Hanken School of Economics

Iran has warned it could close down the strait, through which 20% of the world’s oil transits each day.

Ayatollah Ali Khamenei ruled Iran with defiance and brutality for 36 years. For many Iranians, he will not be revered

Andrew Thomas, Deakin University

Khamenei will largely be remembered for the profound weakness his leadership brought the Islamic Republic.

Despite massive US attack and death of ayatollah, regime change in Iran is unlikely

Donald Heflin, Tufts University

President Trump has appealed to Iranians to topple their government, but a popular uprising is unlikely to defeat current leadership or the Revolutionary Guards, a former US diplomat says.

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