| MS Prodrome: Hope for Earlier Intervention?
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| Jessica Migala |
| Scientists are uncovering that there may be a critical window of opportunity where certain signs and symptoms begin to emerge more than a dozen years before the onset of typical symptoms of MS. This is called the MS prodrome.
The researchers’ most recent data, published in 2025, looked at the 25 years preceding clinical MS symptom onset. They found that the prodrome may appear even earlier than previously suspected, with people visiting their doctor more often starting 14 to 15 years before the first MS symptoms, compared with those who did not have MS.
Overall, the research suggests that these symptoms and health conditions may appear in the MS prodrome: Anxiety, depression, migraine, dizziness, vertigo, insomnia, visual disturbances, osteoarthritis, and knee joint disorders.
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