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17 November, 2025 |
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The Supreme Court said today it won’t review the FDA’s denial of fast-track status for Vanda Pharmaceuticals’ tradipitant in a chronic stomach condition called gastroparesis. Last month, the company had agreed to pause separate, administrative proceedings over its application for gastroparesis until Jan. 7. Meanwhile, the FDA is reviewing the experimental drug for the treatment of
motion sickness, with a decision date of Dec. 30. |
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Alexis Kramer |
Editor, Endpoints News
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Maziar Mike Doustdar, Novo Nordisk CEO (Nichlas Pollier/Bloomberg via Getty Images) |
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by Zachary Brennan
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Novo Nordisk said Monday it will immediately drop its cash-pay prices for megablockbusters Ozempic and Wegovy to $349 per month, more than six weeks before Eli Lilly’s rival weight loss drug Zepbound is expected to match that price. The move is the latest jab by Novo in a long-running competition between the two companies and drug compounders. Both Novo and
Lilly pledged the nearly $150 monthly reduction for cash-paying patients as part of deals made with the Trump administration earlier this month, with discounts made in exchange for Medicare coverage. The cash price of both GLP-1 makers’ injectables will be lowered to $250 per month in two years, according to the Trump administration. Monthly supplies of the tablet versions, if approved by the FDA, will be sold for $150 on the White
House's incoming online pharmacy TrumpRx, which is expected to launch early next year. | |
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by Nicole DeFeudis
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Counsel for Eli Lilly, Novartis and Bristol Myers Squibb told a panel of judges that the government’s rebate pilot program is too limited in scope to address drugmakers’ broader concerns with the 340B system. HHS' Health Resources and Services Administration recently approved applications from nine drugmakers to participate in a pilot that would significantly change the way the 340B discount program operates. For now, it only applies to the 10 drugs that were subject to the first round of Medicare negotiations under the Inflation Reduction Act. “The problem with the pilot program, of course, is it only applies to manufacturers whose drugs have been chosen for drug price negotiation and only to those
drugs,” Catherine Stetson, a Hogan Lovells attorney representing the three drugmakers, said during a Monday oral argument before the US Court of Appeals for the DC Circuit. | |
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by Anna Brown
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Tariffs on branded pharmaceutical products from Switzerland and Liechtenstein will be capped at 15% under a new trade deal with the US, the White House announced. The US will apply whichever is highest out of the "most favored nation" (MFN) tariff rate or a 15% tax on goods originating from the two countries, the Trump administration said on Friday. These levies will not exceed 15% for any products that are subject to future pharma tariffs arising from the Department of Commerce's Section 232 investigation. This latest deal mirrors the details of the US-EU deal announced in July and reflects the Trump
administration's goal of boosting drug manufacturing in the US, with over $480 billion pledged to the country so far this year. | |
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