​

​

​

​Creatine: One of the most well-researched and effective supplements for enhancing muscle strength, cognitive function, and overall energy production, with benefits extending beyond athletes to general health and aging.

It supports brain health, muscle recovery, and even metabolism, making it a simple, safe, and cost-effective addition to nearly anyone’s daily routine.

I take creatine daily. NEVER trust supplements from SCAMazon. Full of fakes with who knows what inside. Buy direct or don't bother.

Creatine 90 Day Jar
​

Time Saved This Week: 13 hours, 23 minutes

​

​NEW Premium Notes​

​Benedict Evans: The Patterns Everyone Else Misses | The Knowledge Project with Shane Parrish​

  • Opinions on AI often land at the extremes: to some, it’s the modern-day nuclear bomb, a force that could unleash irreversible damage, while to others, it promises a future so automated we can finally sit back and relax. However, among all the spicy takes on AI, the rarest and often most controversial is the centrist view. Technology analyst Benedict Evans argues that AI is much more of a platform shift rather than some revolutionary or apocalyptic technology. In these Premium Podcast Notes, he elaborates on his argument by explaining how technology adoption trends tend to work, why training data is not a competitive advantage, why LLMs are (currently) incapable of quantitative analysis, and what the current data says about regular LLM usage

​​
​Food & Supplements for Brain Health & Cognitive Performance | Huberman Lab Essentials
​

  • Your brain runs on what you feed it, so are you giving it the right fuel? In this episode of Huberman Lab Essentials, Dr. Andrew Huberman reveals the nutrients proven to boost brain power, protect cognitive health, and even reshape food cravings. He breaks down exactly how omega-3s, creatine, phosphatidylserine, anthocyanins, choline, and glutamine work, and how to get them from your diet in the right amounts

​

​Adventure as Lasting Happiness – Dr. Arthur Brooks | Jordan B Peterson Podcast​ ​

  • So many of us chase happiness, but what if we’re looking in the wrong place? Jordan Peterson talks with Dr. Arthur Brooks, a Harvard professor and bestselling author, about what it actually takes to live a happy and meaningful life. They discuss why having a clear aim gives life direction, why progress feels better than simply arriving at a goal, and how embracing the adventure of growth can bring lasting satisfaction. Together, they dig into the big questions: what makes life worth living, and how we can align ourselves with it

​

​Upgrade to Premium to Get 3 Premium Notes Every Week, the Full Newsletter, Playable Timestamps, AI Powered Answers, Unlock 500+ Premium Posts, No Ads and MORE​


Go PREMIUM

Top Premium Takeaways Of The Week


​Benedict Evans: The Patterns Everyone Else Misses | The Knowledge Project with Shane Parrish​

“My controversial take on AI is being a centrist”– Benedict Evans
  • AI is a platform shift that everything will be built around for the next 10 to 15 years, but then there will be something else
  • AI is likely going to be more similar to the iPhone (platform shift) than it is to electricity (revolutionary technology)

Be Wary of Fear-Based AI Headlines... [PREMIUM: learn why]​

“To govern is to choose” – Benedict Evans
  • If we govern AI like nuclear weapons, progress will be slow and expensive
  • If we govern AI like social media 2.0, progress could be fast and affordable

Surprising LLM Usage Data: [PREMIUM: see the surprising usage stat]​

  • It’s peculiar that a large number of people only come up with one question per week or month to ask an LLM
  • Shane says that his kids have outsourced basically every question they have (except phone numbers and maps) to an LLM, implying he feels the everyday use stat should be higher

​​
​
​Food & Supplements for Brain Health & Cognitive Performance | Huberman Lab Essentials​

Complete List of Brain-Boosting Nutrients in Order of Importance:

  • EPA fatty acids (omega-3s)
  • Phosphatidylserine
  • ... ​[PREMIUM: complete list]​ ​

Most People Get Enough Omega-6s but Not Omega-3s

  • The best source is [PREMIUM]​, but let’s be real, most of us aren’t...
  • You can also get omega-3s from chia seeds, walnuts, and soybeans
  • If you’re supplementing, aim for [PREMIUM]​ ​

Eggs Are Basically Nature’s Perfect Brain Food (gotta get that choline)

  • Eggs have everything needed for an organism to grow
  • If you don’t eat eggs, you can get some choline from... [PREMIUM]​
  • Aim for [PREMIUM] of choline per day

Creatine Isn’t Just for Gym Bros...

  • it actually helps your brain function better
  • Your brain can use creatine as fuel, and it seems to help with mood and motivation circuits
  • You can get creatine from meat, but if you don’t eat much meat, supplementing makes sense
  • The magic number is [PREMIUM] per day of creatine monohydrate

​

​Adventure as Lasting Happiness – Dr. Arthur Brooks | Jordan B Peterson Podcast​ ​ ​

The “Why” of Life Is About the Meaning of Life; once you discover meaning, you can figure out what direction you should go

  • The direction you choose does not have meaning – it is just the direction
  • This is the difference between strategy and aim

Your Aim Sets Your Emotional Frame: Your brain cannot compute what is positive until it knows... [PREMIUM]​

Learn How to Be Happy: [PREMIUM]​

Looking at Honeybees to Understand Human Happiness:

  • Honeybees perform a waggle dance to tell hive mates where food is, and the richer or closer the nectar source, the faster and more vigorously they dance
  • Similarly, humans tend to [PREMIUM]​

If You Were in Pain, What Would Get You up in the Morning?

  • The answer to this question will help you... [PREMIUM]​

​

Upgrade to Premium to Get 3 Premium Notes Every Week, the Full Newsletter, Playable Timestamps, AI Powered Answers, Unlock 500+ Premium Posts, No Ads and MORE​


Go PREMIUM

​Dr. Michael Snyder: Transform Your Metabolic Health & Longevity by Knowing Your Unique Biology | Huberman Lab​

Taking a Walk After Eating Can Help With Blood Sugar Control

  • If you eat something that spikes your glucose, take a brisk 15-20 minute walk, and that will suppress your spike
  • Your muscles act like glucose scavengers, burning off the excess sugar

Exercise Snacks Are Great for People Who Sit All Day

  • Get up and do air squats or other quick movements
  • Your evolutionary history involved way more daily movement than sitting 8 hours straight

Fat Around Your Organs (Visceral Fat) Is Worse Than Fat Under Your Skin (Subcutaneous Fat)

  • Fat puts stress on your organs, especially your pancreas and beta cells
  • The more obese you are, the higher your inflammation levels typically are

Taking a Walk After Dinner Should Become a Routine...

  • ...not just something you remember to do
  • Dr. Snyder and his wife walk their dog after dinner every night as part of their routine
  • Try not to make your biggest meal dinner if possible
  • People who walk after dinner have lower glucose levels the next day
  • If you go into the evening with a high glucose spike, in general, that correlates with poor sleep

Increase REM: warming your sleeping environment in the last 2 hours dramatically increases REM sleep

  • This tip from Matt Walker helped Huberman get close to 2.5 hours of REM in 6.5-7 hours of sleep

Exercise Is One of the Best Ways to Improve HRV

  • Try deliberate long exhales throughout the day to activate the vagal pathway and slow heart rate
  • This can improve HRV in both waking and sleep states
  • Just remember, periodically, to dump all your air out completely

Your Lifestyle Is by Far Your Biggest Factor

  • Only about 16% of your lifespan is determined by genetics for the average person
  • People in Blue Zones eat diets without much processed food, more Mediterranean/plant-based
    • They eat animal proteins but more fish and chicken, less red meat, lots of vegetables
    • They’re fairly active and have really good social networks
    • They probably sleep pretty well too

​

​All Things Ketones, How to Boost Cognition, Sardine Fasting, Diet Rules, & More | Dr. Dom D’Agostino on The Tim Ferriss Show Ep. 825​

Top 5 Supplements That Everyone Should Take:

  1. CoQ10 – supports heart health & cellular energy production
  2. Creatine Monohydrate – everything, but specifically boosts strength/power output and enhances brain function
  3. Ketones – supports metabolic flexibility & improves mental clarity
  4. Vitamin D – strengthens bone health & supports immune function
  5. Melatonin – regulates sleep cycles & provides antioxidant support

The Best Device for Measuring Ketones: Keto-Mojo Device​

  • This device gives numbers that are more aligned with our biological assays

The Benefits of Supplementing Exogenous Ketones:

  • (1) Quick energy – they give your body a fast fuel source, especially for the brain and muscles
  • (2) Support ketosis – they can help raise blood ketone levels even if you’re not fully on a strict keto diet

Benefits of Fasting: helps to augment the control of the immune system, relaxes the gut and enables the body’s repair processes to occur, reduces the body’s general state of inflammation

The Protocol and Surprising Benefits of ‘Sardine Fasting’:

  • Eat 1-2 cans of sardines per day for one week; can be repeated monthly or as needed. May need to supplement with vitamin C and magnesium
  • Why it helps: Provides essential nutrients and omega-3s while keeping calories/protein low enough to activate autophagy, support immunity, fight brain fog, and promote overall metabolic health

Movement Is Critical for Optimal Metabolic Health; get outside and walk first thing in the morning, and try to move after dinner for the sake of glucose metabolism

Why Dom Takes Melatonin (5-10 mg)

  • Melatonin is an endocrine function (including testosterone production) in hibernating animals, but not in humans
  • Huberman references animal studies when cautioning against melatonin use, but not human studies
  • Dom takes melatonin not to sleep, but as a neuroprotective agent that has beneficial effects for the brain, including combating Alzheimer’s disease
  • While specific animals are sensitive to melatonin, it appears to be beneficial for humans

​

​