Endpoints News
Inhibrx eyes OX40 agonist-cancer vaccine studies Read in browser
Endpoints News
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8 September, 2026
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top stories
1. Bristol Myers claims Phase 2 success for GPRC5D-directed CAR-T
2. Inhibrx opens door to cancer vaccine combo for its OX40 agonist
3. Moonwalk raises $70M to test siRNA treatment for obesity
4.
news briefing
Krazati withdrawal completed; Wegovy trial meets endpoint for kids ages 6 to 12
5. Updated: Novartis sinks after second disastrous trial failure, this time of Avidity-acquired drug
6. Roivant reports Phase 2 win for lung disease drug that it got from Bayer
7. BrainChild Bio gets $116M for pivotal trial of pediatric brain tumor CAR-T
8. Beam says AATD base editing data hold up after one year
9. Diabetes cell therapy biotechs Sernova and Seraxis to merge
more stories
 
 
Karen Weintraub
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Some unlucky blood cancer patients progress even after CAR-T therapy — and they’ve had few treatment options. Now, a Bristol Myers Phase 2 trial success offers them hope. A CAR-T treatment nicknamed arlo-cel improved response rates for heavily treated multiple myeloma patients, as Max Gelman reports.

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Karen Weintraub
Deputy Editor, Endpoints News
1
by Max Gelman

CAR-T ther­a­py has rev­o­lu­tion­ized blood can­cer treat­ment, par­tic­u­lar­ly in mul­ti­ple myelo­ma. But an on­go­ing con­cern re­mains: If pa­tients’ can­cers progress af­ter re­ceiv­ing CAR-T, what oth­er...

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Mark Lappe, Inhibrx CEO
2
by Reynald Castaneda

In­hi­brx Bio­sciences says its lat­est mid-stage re­sults show the po­ten­tial of its OX40 ag­o­nist in im­muno­genic can­cers — but al­so its prospects in com­bi­na­tion with...

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Alex Aravanis, Moonwalk Biosciences CEO
3
by Lei Lei Wu

Moon­walk Bio­sciences is head­ing to the clin­ic with an obe­si­ty pro­gram and has raised $70 mil­lion for that goal, lean­ing in­to a shift in its...

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News Briefing: Quick hits from the biopharma web
4
by ENDPOINTS

Plus news about Struc­ture Ther­a­peu­tics, Clover­leaf Bio and Wind­ward Bio.

FDA fi­nal­izes Kraza­ti with­draw­al: Reg­u­la­tors of­fi­cial­ly fi­nal­izedthe drug’s with­draw­al in sec­ond-line col­orec­tal can­cer last...

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5
by Elizabeth Cairns

In the wake of its high-pro­file set­back in heart dis­ease late last week, No­var­tis re­al­ly need­ed a win.

It didn’t get one.

The Swiss phar­ma...

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