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28 August, 2026
THE BANK THAT TAKES YOU FROM SEED STAGE TO WORLD STAGE
J.P. Morgan was the right banking team for Montara Therapeutics. Founder Nicholas Hertz trusted the team’s life sciences expertise, security, and support to focus on what mattered most.
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top stories
1. BioNTech, Genentech terminate Phase 2 of personalized mRNA cancer vaccine
2. Roche bets $1B+ on DualityBio's ADC tech to tackle payload resistance
3. Future of AstraZeneca’s gene silencer in heart disease uncertain after trial failure
4.
news briefing
Mounjaro scores FDA approval to reduce CV risk; Teva to buy an approved drug
5. Roivant’s road to a potential blockbuster begins with FDA approval for Lisraya
6. Gilead gets another HIV treatment approval, extending lenacapavir's dominance
7.
peer review
Daiichi Sankyo to give commercial team a makeover; Novo Nordisk's GPCR partner finds CMO
more stories
 
Karen Weintraub
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BioNTech and Genentech terminated a Phase 2 trial of their personalized mRNA cancer vaccine in certain colorectal cancer patients. The failure in that 'cold' tumor, as Kyle LaHucik explains, comes only a week after Moderna and Merck’s success in a 'hot' tumor with their own cancer vaccine for the more-immune-vulnerable melanoma.

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Karen Weintraub
Deputy Editor, Endpoints News
1
by Kyle LaHucik

BioN­Tech has axed a Phase 2 tri­al of its per­son­al­ized mR­NA can­cer vac­cine just a week af­ter Mod­er­na and Mer­ck had break­out suc­cess for their...

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2
by Ayisha Sharma

Du­al­i­ty­Bio saidFri­day it will re­ceive $45 mil­lion up­front from Roche’s Genen­tech to de­vel­op drugs that could be part of a new wave of an­ti­body-drug...

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ESC Congress in Munich (Elizabeth Cairns for Endpoints News)
3
by Elizabeth Cairns

MU­NICH— The sur­prise fail­ure of a high-pro­file study of As­traZeneca and Io­n­is Phar­ma­ceu­ti­cals’ Wain­ua can be at­trib­uted to pa­tients in the tri­al al­so tak­ing...

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News Briefing: Quick hits from the biopharma web
4
by ENDPOINTS

Plus news about Aus­per­Bio and Sam­sung Bi­o­log­ics.

Eli Lil­ly’s Moun­jaro wins heart ap­proval: The block­buster drug, whose gener­ic name is tirzepatide, was ap­proved on Fri­day...

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women in BIOPHARMA '26 - Register Now
Twenty new honorees join the 140-plus women Endpoints News has recognized for reshaping biopharma. How did they get there, and what's changed? Join us for exclusive interviews, in-depth profiles and a frank look at gender representation in the industry today. Register now.
5
by Max Bayer

The FDA ap­proved Roivant’s der­mato­myosi­tis drug bre­poc­i­tinib on Thurs­day, the first ma­jor reg­u­la­to­ry nod that could ush­er in a multi­bil­lion-dol­lar rev­enue stream for the hub-and-spoke...

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6
by Kyle LaHucik