The next batch of Great Britain Mandatory Classification and Labelling (GB MCL) technical reports is now available for download.
A GB MCL technical report is an independent scientific evaluation of the information submitted under the standalone GB MCL process or as part of the EU harmonised classification and labelling process.
It sets out whether there is adequate scientific evidence to support a new or revised GB MCL of a substance and what that GB MCL should be.
Download the next batch of technical reports from the GB MCL publication table.
These GB MCL technical reports relate to substances for which the Committee for Risk Assessment (RAC) published a RAC Opinion under Article 37(4) of EU CLP during 2025, based on information submitted under the EU CLP Regulation. The scientific information supporting the RAC Opinion is evaluated under the GB MCL system.
At the time of publication, the classification and labelling proposed in these technical reports have not been agreed and/or adopted in GB.
For information on the next steps in the process, please see our webpage on the GB MCL system.
We expect to publish our next batch of technical reports in late May 2026. Chemical classification, labelling and packaging (CLP) ebulletin alerts will be issued when technical reports are published on the HSE website.
If your business is affected by the GB CLP Regulation, please also consider if you are likely to be affected by the classification and labelling proposals.
Contact us
Journalists should contact HSE’s press office for further information.
If you have any questions or feedback on the GB MCL technical reports, contact HSE at GBCLP.GBMCL@hse.gov.uk.
Call for comments
The GB MCL process includes the consideration of information gathered from public consultations, conducted by HSE or international bodies such as the European Chemicals Agency (ECHA).
ECHA has announced public consultations on the following proposals for harmonised classification and labelling (CLH):
Deadline: 22 June 2026
- maleic acid; (2Z)-but-2-enedioic acid (EC: 203-742-5; CAS: 110-16-7). Chemical registered under REACH. Health hazard classes open for commenting
- Swinglea glutinosa (Rutaceae) leaves extract using ethanol and water (EC: -; CAS:-). Pesticide active substance. All hazard classes open for commenting
Deadline: 26 June 2026
- 1-isopropyl-2,2-dimethyltrimethylene diisobutyrate (EC: 229-934-9; CAS: 6846-50-0). Chemical registered under REACH. Health hazard classes open for commenting
- chloroethane (EC: 200-830-5; CAS: 75-00-3). Chemical registered under REACH. Health and environment hazard classes open for commenting
- N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide (EC: 435-860-1; CAS: 214417-91-1). Chemical registered under REACH. Environment hazard classes open for commenting
- N-ethyl-N-[2-[1-(2-methylpropoxy)ethoxy]ethyl]-4-(phenylazo)aniline (EC: 252-021-1; CAS: 34432-92-3). Chemical registered under REACH. Environment hazard classes open for commenting
- silver chloride (EC: 232-033-3; CAS: 7783-90-6). Biocide active substance All hazard classes open for commenting
Deadline: 3 July 2026
- 2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclooctane; metaldehyde (EC: 203-600-2; CAS: 108-62-3). Pesticide active substance. Health and environment hazard classes open for commenting
- variable domain of camelid heavy-chain antibody (VHH protein, C577H905N169O177S4), against lipid cell membrane of fungi, obtained by fermentation in Komagataella phaffii (Phaffomycetaceae); [ASFBIOF01-02] (EC: -; CAS:-). Pesticide active substance. All hazard classes open for commenting
Deadline: 10 July 2026
- Cobalt bis(2-ethylhexanoate) (EC: 205-250-6; CAS: 136-52-7). Chemical registered under REACH. Health hazard classes open for commenting
- cobalt dihydroxide [1], cobalt(2+) propionate [2], cobalt(II) 4-oxopent-2-en-2-olate [3] (EC: 244-166-4 [1]; 216-333-1 [2];237-855-6 [3]; CAS: 21041-93-0 [1]; 1560-69-6 [2]; 14024-48-7 [3]). Chemical registered under REACH. Health hazard classes open for commenting
- Cobalt oxide (EC: 215-154-6; CAS: 1307-96-6). Chemical registered under REACH. Health hazard classes open for commenting
View the consultations on the ECHA website.
UK-based businesses with an interest in the proposal are strongly encouraged to share any relevant information.
Scientific and technical information should be submitted directly to ECHA using their commenting webform by the deadline above.
All comments will be published on ECHA's website.
Further information
If your business is affected by the GB CLP Regulation, please also consider if you are likely to be affected by the classification and labelling proposals.
Let us know at an early stage if you anticipate any significant impacts or benefits.
Information on wider policy and impact considerations can be submitted to HSE at GBCLP.GBMCL@hse.gov.uk.
Under the GB CLP Regulation, HSE will consider all published opinions of the Committee of Risk Assessment of ECHA (RAC) before publishing its own Agency Technical Reports and Agency Opinions, so any information you provide will be important in any final GB MCL decision.
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