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5 May, 2026
US Pharma and Biotech Summit - May 14, 2026
US biopharma still leads the world in high-risk drug development, but the road from innovation to access has never been harder to predict. Hear from top executives and investors on how they’re navigating what’s next. Join us.
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top stories
1. Pfizer's Albert Bourla on mega-merger prospects: 'No'
2. BioNTech to scale down manufacturing, over 1,800 jobs on the line
3. Intercept's next-gen FXR agonist fails Phase 2 in latest setback for Italian-owned pharma
4. Pfizer cuts final Trillium-related program, but R&D spend jumps on cancer, obesity studies
5. Updated: Madrigal extends MASH deal streak with Arrowhead drug that J&J didn't want
6. Cytokinetics succeeds where Bristol Myers failed in heart muscle disease
7. Swiss manufacturing, biotech industry so far unfazed by geopolitics
8.
news briefing
Second life for a gene therapy; Takeda passes Phase 2/3 test; UK cancer biotech's $83M raise
more stories
 
Lydia Ramsey Pflanzer
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One comment in Pfizer's earnings call this morning stuck out to Max Bayer: "If you’re asking me if right now we think that we are going to go for something very big, a big merger? No,” CEO Albert Bourla said.

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Lydia Ramsey Pflanzer
Deputy Editor, Endpoints News
Albert Bourla, Pfizer CEO (Michael Nagle/Bloomberg via Getty Images)
1
by Max Bayer

The most can­did man in phar­ma strikes again.

When asked on Tues­day’s earn­ings call whether Pfiz­er would con­sid­er a “trans­for­ma­tive M&A” deal in the near...

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2
by Ayisha Sharma

BioN­Tech is mak­ing big cuts to its man­u­fac­tur­ing foot­print.

The Ger­man com­pa­ny said in its first-quar­ter earn­ings re­leasethat up to 1,860 man­u­fac­tur­ing staff could...

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3
by Kyle LaHucik

In­ter­cept Phar­ma­ceu­ti­cal­s' at­tempt at cre­at­ing a next-gen­er­a­tion FXR ag­o­nist for cer­tain forms of liv­er in­flam­ma­tion ap­pears to have end­ed.

The drug de­vel­op­er's INT-787 showed "no...

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4
by Max Bayer

Pfiz­er has dis­con­tin­ued the fi­nal clin­i­cal study stem­ming from its 2021 ac­qui­si­tion of Tril­li­um Ther­a­peu­tics, fun­nel­ing cash pri­mar­i­ly to­ward a host of oth­er can­cer and...

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5
by Kyle LaHucik

Madri­gal Phar­ma­ceu­ti­cals has made its fourth MASH deal in 10 months, fur­ther sig­nal­ing its am­bi­tions to be not just the first drug­mak­er for the fat­ty...

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6
by Elizabeth Cairns

Cy­to­ki­net­ics&