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10 October, 2025 |
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President Donald Trump later today is expected to announce a second "most favored nation" drug pricing deal, this time with AstraZeneca. Trump announced a deal with Pfizer just last week. Stay tuned for more after 5 p.m. ET! |
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Alexis Kramer |
Editor, Endpoints News
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by Jared Whitlock
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The Biosecure Act has another chance in Congress after the Senate passed a new version this week. But the latest iteration stops short of targeting WuXi AppTec and WuXi Biologics, key fixtures in US drugmakers’ supply chains. The Senate voted on Thursday to attach Biosecure as an amendment to the annual defense policy bill. It seeks to curb
US biotechs’ reliance on Chinese suppliers over national security concerns. Unlike last year’s proposal, which explicitly named the WuXi companies and others in China, the revised bill limits its scope to companies tied to China’s military based on existing government watch lists. Those include BGI Group and MGI Tech, but not the WuXi entities. |
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by Max Gelman
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Johnson & Johnson is reportedly in talks to acquire a partner that’s developing a linchpin of its future immunology plans. J&J and Protagonist Therapeutics are in discussions for a buyout, the Wall Street Journal reported Friday, citing people familiar with the matter. The exact parameters of the deal were not disclosed, and it’s not certain that a deal will take place. Protagonist’s stock PTGX surged Friday morning by more than 35%, rising above $90 per share for the first time in the company’s history. As of Thursday’s market close, Protagonist had a market cap of $4.06 billion. A spokesperson for Protagonist told Endpoints News in an email that the
company “doesn’t comment on speculation or rumor.” A J&J spokesperson didn’t immediately respond to a request for comment. |
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Pascal Soriot, AstraZeneca CEO (Justin Tallis/Press Association via AP Images) |
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by Max Bayer
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The White House and AstraZeneca are expected to announce a deal on drug pricing later Friday, according to people familiar with the matter, as President Donald Trump strikes a second agreement under his "most favored nation" push. A White House official confirmed to Endpoints News that there would be a drug price announcement around 5 p.m. ET Friday, but
declined to say which company or companies would be there, if any. Rumors of AstraZeneca's deal were coursing through Washington Friday, as the industry speculated about who would announce next. An AstraZeneca spokesperson declined to comment. On Thursday, the company's CEO Pascal Soriot and Virginia Governor Glenn Youngkin broke ground on a $4.5 billion investment on a new manufacturing site. The company
has pledged $50 billion in new investment in the US. |
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by Max Bayer
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The head of the FDA office that helps determine orphan drug designations has been reassigned and is no longer in the role, an administration official confirmed to Endpoints News. Sandra Retzky, director of the Office of Orphan Products Development, is no longer in the role but she has not been fired, the source told Endpoints on Friday. It
wasn't clear to where Retzky was reassigned, and she didn't respond to multiple attempts to reach her for comment. The orphan drug job sits within the office of the FDA's chief medical offi&s |
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